The Manganese Health Research Program (MHRP) was initiated in 2003 by the International Manganese Institute.

Committed to launching an ambitious research program on the effects of manganese on human health, it was important to move forward in partnership with an organization that shared a strong interest in filling the knowledge gaps in this area. IMnI’s partner, the US Military Operational Medicine Research Program funded the program with over $5 million dollars for research.

The MHRP Process

The MHRP was spearheaded by a team comprised of government, academia, world-renowned scientists and researchers, and US and international industry. This Steering Committee was chaired by the IMnI, while Dr. Michael Aschner of Vanderbilt University oversaw and administered the entire multi-study program. The collaborative effort sought to clarify the level at which exposure to manganese may play a role in adverse health effects. The program objective was to protect the health of those exposed to manganese through their work by developing an improved understanding of the relationship between exposure and health effects.


The program saw 20 different studies with over 150 published peer-reviewed articles, abstracts and presentations involving some 100 scientists from around the world. Much of the research was previewed at the “Mn Health Research Program Showcase Conference: New Discoveries – New Directions”, held outside Washington, D.C. in June 2009. Based on the work presented, a panel of experts (coming from academia, regulatory bodies and industry) concluded by proposing further avenues of research on Mn and human health.

Some new findings from the MHRP program are still being published in peer-reviewed journals today. For more about the Manganese Health Research Program and the studies it generated, please contact hse@manganese.org